Japanese Scientists Claim Breakthrough in Deleting Chromosome Linked to Down Syndrome

A group of researchers in Japan have reportedly made a groundbreaking claim of successfully removing the extra chromosome responsible for Down syndrome in human cells. The scientists, working at a major genetics institute in Tokyo, say they used advanced genome-editing techniques to delete the third copy of chromosome 21, which causes the condition.

According to preliminary findings released by the team, the experiment was conducted on cultured cells derived from individuals with Down syndrome. The scientists employed CRISPR-Cas9-based technologies to target and eliminate the additional chromosome, restoring the cells to a typical chromosomal structure. While the development is still in its early stages, the researchers described the results as "promising" and said the work could pave the way for future therapeutic options.

There are currently no plans to attempt similar modifications in living humans or embryos, as ethical and technical challenges remain substantial. Down syndrome, also known as trisomy 21, is a genetic disorder that affects about 1 in 700 births globally and is currently managed through supportive therapies, not cures.

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